The researchers concluded that depression and memory were closely interrelated, with both seeming to affect each other.
Depressive symptoms are linked to subsequent memory decline in older people, while poorer memory is also linked to an increase in depressive symptoms later on, according to a new study led by researchers at UCL and Brighton and Sussex Medical School.
"It also suggests that interventions to reduce depressive symptoms may help to slow down memory decline." The research team suggested that depression might affect memory due to depression-related changes in the brain. These include neurochemical imbalances , structural changes in regions involved in memory processing, and disruptions to the brain's ability to re-organise and form new connections.
Dr Cadar added:"Depression can cause changes in brain structures, such as the hippocampus, which is critical for memory formation and retrieval. Chronic stress and high levels of cortisol associated with depression can damage neurons in these areas. However, a further understanding of mechanisms linking memory decline and depression is crucial for developing targeted interventions aimed at improving mood and slowing cognitive decline in individuals with depression and memory impairment.
In addition, participants who experienced more of an increase in depressive symptoms during the study were more likely to have a steeper memory decline at the same time, and vice versa -- those who had a steeper memory decline were more likely to have a sharper increase in depressive symptoms. The study and its authors received support from the National Institute on Aging, the Economic and Social Research Council , the National Institute for Health and Research , Alzheimer's Society UK, and Alzheimer's Research UK.Researchers have leveraged a complex web of data to test a hypothesis: That structural racism is associated with resources and structures at the neighborhood level that are closely associated with ...
Alzheimer's Research Healthy Aging Arthritis Memory Depression Dementia Mental Health
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