Adults diagnosed with clinical depression after type 2 diabetes onset had more A1c variability compared with people with type 2 diabetes and no depression or with depression predating their diabetes.
levels compared with patients diagnosed with MDD before they developed type 2 diabetes and with those who never had MDD.
The findings suggest that clinicians need to monitor mean A1c levels over time in patients with type 2 diabetes and also closely monitor within-patient variability in A1c levels, especially when the patient receives a diagnosis of MDD following a diagnosis of type 2 diabetes., which prospectively enrolled UK residents who were aged 40-69 years during the period 2006 to 2020.
They also identified subjects with MDD based on a history of an MDD diagnosis at least twice in their medical records. They divided the subjects into three groups: diabetes without MDD, a diagnosis of MDD before the diabetes diagnosis, or MDD diagnosed after diabetes diagnosis.The longitudinal analysis sample consisted of 9264 eligible patients with type 2 diabetes, followed for a median of 7.
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