The DeepMind program AlphaFold predicted the structures.
The artificial intelligence group DeepMind has unraveled the structures of nearly every protein known to science.
"It took us quite a long time to go through this massive database of structures, but [it] opened this whole array of new three-dimensional shapes we’d never seen before that could actually break down plastics," John McGeehan, a professor of structural biology at the University of Portsmouth in the U.K., told The Guardian."There’s a complete paradigm shift. We can really accelerate where we go from here — and that helps us direct these precious resources to the stuff that matters.
Scientists do have ways to visualize proteins and analyze their structures, but this is slow and difficult work. The most common way to image proteins is through X-ray crystallography, according to the journal Nature , which involves beaming X-rays at solid crystals of proteins and measuring how those rays are diffracted to determine how the protein is arranged. This experimental work had established the shape of about 190,000 proteins, according to DeepMind .
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DeepMind AI Powers Major Scientific Breakthrough: AlphaFold Generates 3D View of the Protein UniverseAI-powered predictions of the three-dimensional structures of nearly all cataloged proteins known to science have been made by DeepMind and EMBL’s European Bioinformatics Institute (EMBL-EBI). The catalog is freely and openly available to the scientific community, via the AlphaFold Protein Structure
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