Women can wait up to two years to be diagnosed with the condition, a researcher looking for its cause told 'Newsweek.'
by enlarged ovaries— which may have fluid-filled sacs surrounding the eggs—irregular periods and high levels of the hormone androgen. As well as issues with menstruating—which can cause problems getting pregnant—those with PCOS are also more likely to develop type 2 diabetes and high cholesterol, have excess hair on the body and face, thin hair on the head, develop acne and gain weight.
To find out more about the potential mechanism behind this link, the team also studied mice with PCOS-like traits. They found mice exposed to androgen hormones in the womb were more likely to give birth to babies with the condition. This was passed on for up to three generations. Co-author Elisabet Stener-Victorin, professor in the Department of Physiology and Pharmacology at Sweden's Karolinska Institutet, explained toIn a separate study, they showed that women with the condition have higher levels of androgens, irregular menstrual cycles, and abnormally shaped ovaries. PCOS patients also had a higher chance of being insulin resistant, and having enlarged fat cells independent of obesity, as well as differences in their fat and muscles related to gene expression.
"This study indicates that it is rather intrauterine/germ cell factors than genetic factors that contribute to the development and transmission of the disease," Stener-Victorin explained.
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