Chinese scientists insert human brain gene into monkeys, sparking ethical debate. - NBCNewsMACH
. And since the human and monkey versions of MCPH1 are slightly different, scientists think the gene may be partly responsible for humans’ high intelligence.In the study, the scientists added the human version of MCPH1 to 11 embryos that would become rhesus macaques, dirty-blond monkeys that share about 93 percent of their DNA with humans. The so-called transgenic embryos were then implanted in the wombs of female monkeys.
The transgenic monkeys behaved much like their unaltered counterparts, and their brains were roughly the same size. But their brain cells took longer to develop compared to those of the unaltered monkeys — a sign that the researchers interpreted as neoteny, the super-slow maturation of the human brain that is thought to be linked to our species’ high intelligence.
“Rhesus monkeys are far enough evolutionarily from humans that a few additions of genes will not create a 'Planet of the Apes' scenario,” she said, referring to fears that the transgenic monkeys could be self-aware.Rhesus monkeys and other Old World monkeys can be a useful model for studying the human brain. Their brains resemble humans’ brains much more closely than those of other common research animals, such as mice.
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