Diagnosis of kidney allograft rejection is complex & somewhat subjective; but an automated version of the BanffClassification could streamline assessment & improve diagnostic accuracy. News and Views from NadaAlachkar & Nissrin Alachkar HopkinsMedicine
To diagnose and treat rejection in kidney transplant patients, clinicians rely primarily on pathological findings from kidney biopsies, which are reviewed by renal pathologists. The treatment approach depends on the specific type of rejection.
In cases of T cell-mediated rejection, mild cases may only require optimization of the existing immunosuppressive regimen, whereas severe cases may require more potent immunosuppression with rabbit anti-thymocyte immunoglobulin.
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