AstraZeneca, Merck score win with Lynparza approval for pancreatic cancer

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AstraZeneca, Merck score win with Lynparza approval for pancreatic cancer
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AstraZeneca and Merck's ovarian cancer drug Lynparza has received U.S. regu...

AstraZeneca and Merck’s ovarian cancer drug Lynparza has received U.S. regulatory approval for the treatment of advanced pancreatic cancer, cementing its lead in a niche category of cancer treatments.

Mutations in BRCA genes impair the ability to repair DNA damage and are typically linked with breast and ovarian cancers, but can occur in other cancers as well. It is already approved for ovarian and breast cancers, and its latest approval underscores the potential of PARP inhibitors for use in newer indications.

Lynparza became the first marketed PARP drug with a U.S. approval for ovarian cancer in 2014 and is key to AstraZeneca’s push in oncology and sustaining the company’s turnaround.

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