Researchers are looking to see if GLP-1 receptor agonists, DPP4 inhibitors, and SGLT2 inhibitors have beneficial effects in osteoarthritis.
"Hormone-based weight loss drugs are a game changer" for obesity management, Sébastien Czernichow, MD, PhD, said during a plenary session at the, added Czernichow, who is professor of nutrition at Paris Cité University and head of the Department of Nutrition at the George Pompidou European Hospital in Paris, France.
"The real question is: Are we able to fund these drugs for everyone? Or will only the richest patients be allocated to these drugs?" Czernichow said., MBBS, PhD, professor of musculoskeletal biology and an honorary rheumatologist at The Kennedy Institute of Rheumatology at University of Oxford in Oxford, England, was concerned about rebound weight gain.
"You mentioned that the double-digit weight loss is getting very close to the results from bariatric surgery, but bariatric surgery you do once, and for these drugs, to maintain the weight loss, you need to take them continuously," she said.Yet another delegate cautioned on the potential effects of significant weight loss on bone and cartilage.
Although these drugs are considered"weight neutral," in vitro studies have suggested that the DPP4 enzyme may have a role to play in chondrocyte survival and inflammation, Yu-Hsiu Chen, of the Tri-Service General Hospital and the National Defense Medical Center in Taipei, Taiwan, toldwhere we found the concentration of DPP4 in the synovial fluid was correlated with radiographic change in knee OA," Chen said.
Chen and colleagues concluded:"These results strongly indicate that DPP4 inhibitors could be considered as a viable treatment approach for individuals with type 2 who are at risk for developing OA or already have OA.
Generalized Osteoarthritis OA - Osteoarthritis DJD - Degenerative Joint Disease Degenerative Arthritis Generalised Osteoarthritis Osteoarthritis (OA) Diabetes Mellitus Type 2 Diabetes Mellitus Type Ii Type 2 Diabetes Type 2 DM T2DM T2D GLP-1 Receptor Agonists Glucagon-Like Peptide-1 Receptor Agonists Weight Management Obesity Obese Weight Loss
Indonesia Berita Terbaru, Indonesia Berita utama
Similar News:Anda juga dapat membaca berita serupa dengan ini yang kami kumpulkan dari sumber berita lain.
Americans plugged into drugs to fight weight, diabetesAbout 12% of all Americans have taken Ozempic or another GLP-1 drug, according to a new survey released Friday by health policy research nonprofit KFF.
Baca lebih lajut »
Denmark to Restrict Ozempic, Other GLP-1 Drugs, to Treat Type 2 DiabetesDenmark will start putting patients suffering from type 2 diabetes on cheaper drugs before prescribing so-called GLP-1 drugs such as Novo Nordisk's Ozempic, the Danish...
Baca lebih lajut »
Popular Weight Loss and Diabetes Drugs May Also Help Alleviate Sleep Apnea SymptomsCertain weight loss and diabetes medications, including tirzepatide (Zepbound, Mounjaro) and semaglutide (Ozempic, Wegovy), may help people sleep better. This is because losing weight can ease symptoms of sleep apnea, which can then result in a more restful night.
Baca lebih lajut »
Cybersecurity Firm Takes Down 250 Websites Selling Fake Weight-Loss and Diabetes DrugsBrandShield, a cybersecurity firm, has successfully shut down over 250 websites that were selling counterfeit versions of popular weight-loss and diabetes drugs in the GLP-1 class. The majority of these websites were related to GLP-1 medicines, which are used to treat metabolic conditions and also aid in weight loss.
Baca lebih lajut »
Updates on Headache, Migraine, and Antiepileptic Drugs During PregnancyChristoph Diener provides recent updates on headache in children, migraine drugs, and antiepileptic drugs during pregnancy
Baca lebih lajut »
Ozempic-Like Drugs Could Help Manage Addiction to Drugs And AlcoholThe Best in Science News and Amazing Breakthroughs
Baca lebih lajut »