A new imaging approach monitors antibody responses to vaccines more quickly than current techniques, which could accelerate vaccine design
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Looking at the ratio of useful “on-target” to less useful “off-target” antibodies resulting from vaccination helps us to optimise the vaccine to tip the response towards more protective antibody production, says Ward. The next day, they imaged the antibody-bound antigens in each sample in bulk, which produced detailed maps of the different antibody structures in the samples and how they bound to the antigen.
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