Science, Space and Technology News 2024
The new study has found the genes that significantly increase a person’s risk of developing multiple sclerosis were introduced into north-western Europe around 5,000 years ago by sheep and cattle herders migrating from the east. Credit: SayoStudio
Northern Europe has the highest prevalence of multiple sclerosis in the world. A new study has found the genes that significantly increase a person’s risk of developing multiple sclerosis were introduced into north-western Europe around 5,000 years ago by sheep and cattle herders migrating from the east.
“It must have been a distinct advantage for the Yamnaya people to carry the MS risk genes, even after arriving in Europe, despite the fact that these genes undeniably increased their risk of developing MS,” said Professor Eske Willerslev, jointly at the Universities of Cambridge and Copenhagen and a Fellow of St John’s College, an expert in analysis of ancient DNA and Director of the project.
From a genetic perspective, the Yamnaya people are thought to be the ancestors of the present-day inhabitants of much of North-Western Europe. Their genetic influence on today’s population of southern Europe is much weaker. Professor Lars Fugger, a co-author of the MS study professor and consultant physician at John Radcliffe Hospital,, said: “This means we can now understand and seek to treat MS for what it actually is: the result of a genetic adaptation to certain environmental conditions that occurred back in our prehistory.”
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