New study reveals drivers of rare cancer and provides a possible alternative solution to surgery. The genetic code of a rare form of kidney cancer, called reninoma, has been studied for the first time. In the new paper, published today (September 25th) in Nature Communications, researchers at the
Researchers have decoded the genetic makeup of the rare kidney cancer, reninoma, for the first time. Collaborating institutions identified an error in thecancer gene as the cause. Using advanced genomic techniques, the team believes existing drugs targeting this gene could treat reninoma without surgery.The genetic code of a rare form of kidney cancer, called reninoma, has been studied for the first time.
Taryn Treger, first author of the study and The Little Princess Trust Fellow at the Wellcome Sanger Institute, said: “Many cancerous tumors have already been deciphered with genomic technologies, however, this is not so true in rare cancers, particularly those affecting children. Our work aims to fill that gap. This is the first time that we have identified the drivers for reninoma and we hope that our work continues to pave the way towards new therapies for childhood cancers.
Dr. Sam Behjati, co-lead author of the study, Wellcome Senior Research Fellow at the Wellcome Sanger Institute and Honorary Consultant Paediatric Oncologist at Addenbrooke’s Hospital, said: “Rare cancers are exceedingly challenging to study, and patients with such tumors may therefore not benefit from cancer research.
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