Accelerating Drug Development With New Way of Identifying Proteins — All living cells contain p |
The illustration shows how different areas of PRC2 protein bind to survivin. The researchers chopped the PRC2 sequence into units of 15 amino acids and arranged them on a grid. Each pixel in that grid is 1 unit. The color shows binding strength to survivin. Blue means the unit in that pixel doesn’t bind/binds weakly to survivin, and the bright pink pixels are the strongest binders.
Currently, the general view is that each protein’s structure is what controls its function in cells. The atomic sequences, meaning how the atoms are arranged in the proteins, create the protein’s structure and shape. But there are many proteins that lack a well-defined structure.has developed a new method where proteins are scanned based on the number of they contain in order to identify them and their function instead of identifying them based on their structure.
The researchers see advantages to this method of scanning proteins. Machine learning also speeds up the process of linking the number and type of amino acids to a certain function. This in turn means that the development of new biological drugs can be accelerated.
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