Glioblastoma is one of the most common and aggressive forms of brain cancer, and it's one of the hardest to treat.
A newly developed hydrogel, tested on mice, cleaned up traces of glioblastoma tumors and stopped them from returning. The hydrogel was so effective that there was a"striking" 100 percent survival rate in the animals.
is the chemotherapy drug at the center of the gel, used to make nano-sized filaments for insertion into the brain. The drug is already approved for treating other cancers, including breast and lung cancer.The hydrogel covers the cancer cavity and the thin grooves left by tumor removal evenly, releasing an
"Thinking that there is potential for this new hydrogel combination to change that survival curve for glioblastoma patients is very exciting." Researchers describe the strategy as a"drug-delivered-by-drug", and in the tests, it seemed to boost the animals' immune systems. When glioblastoma tumors were reintroduced, the mice could fight them off on their own, without further treatment.
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