A specific strain of viruses could be our cure.
The scientist from the laboratories of Elizabeth Villa, Kevin Corbett, and Joe Pogliano found that Elizabeth Villa, Kevin Corbett, and Joe Pogliano found that jumbo phage cells construct a shielded compartment that acts similar to a nucleus in human and animal cells and protects the virus's core genetic material, which is needed to replicate and spread.
The team also characterized the nucleus-like compartment for the first time and used leading technologies such as cryo-electron microscopy and tomography to get the most accurate result. "It's a different kind of compartment—unlike anything we have ever seen in nature," said Villa, an associate professor in the UC San Diego School of Biological Sciences and a Howard Hughes Medical Institute Investigator. "We were able to characterize this compartment—how it assembles and functions at the most basic level—from each atom to the scale of the entire organism."According to Assoc. Prof.
"As we move toward the development of phage therapies, we'll need to learn more about this newly discovered phage nucleus since it appears to make them better at attacking bacteria," said Pogliano. The researchers, including Pogliano and Villa, also plan to collaborate with experts at UC San Diego's Center for Innovative Phage Applications and Treatments, the first dedicated phage therapy center in North America.
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