A healthy lifestyle may offset genetic risk for Alzheimer's

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A healthy lifestyle may offset genetic risk for Alzheimer's
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A healthy lifestyle can cut your risk of developing Alzheimer's or other forms of dementia even if you have genes that raise your risk for these mind-destroying diseases, a large study has found.

A healthy lifestyle can cut your risk of developing Alzheimer's or other forms of dementia even if you have genes that raise your risk for these mind-destroying diseases, a large study has found.

Results were discussed at the Alzheimer's Association International Conference in Los Angeles and published online by the Journal of the American Medical Association. Dr. Elzbieta Kuzma and colleagues at the University of Exeter Medical School in England used the UK Biobank to study nearly 200,000 people 60 or older with no signs or symptoms of dementia at the start. Their genetic risk was classified as high, medium or low based on dozens of mutations known to affect dementia. They also were grouped by lifestyle factors.

One limitation: Researchers only had information on mutations affecting people of European ancestry, so it's not known whether the same is true for other racial or ethnic groups.

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