Phase-1 trials of a brain injection achieve over 90 percent reduction in seizures in two patients.
Their condition has drastically improved in the last year, and it seems like they made the right choice so far. The cell therapy has also raised hopes for millions of other patients whose lives are severely affected by epilepsy.Epilepsy develops due to an imbalance between excitatory and inhibitory neuron activity.
An imbalance between excitatory and inhibitory neurons can result in seizures, memory loss, and otherThis brain injection contains a high-concentration dose of lab-grown inhibitory neurons developed from human embryonic stem cells. It brings down the overall action potential and eventuallyWithin one year of NRTX-1001 treatment, the first patient who used to have 32 seizures a month experienced a 95 percent decline in monthly seizures.
“Although our clinical investigation is ongoing in additional patients, it is gratifying to witness the first two patients achieving seizure relief without additional cognitive impairment to date, which supports the therapeutic potential of NRTX-1001,” said Nicholas.
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