Converting cancerous cells 'back into their normal state'. 🩸 engineering
Early-stage pancreatic cancer has a 'reset button'
"These findings open up the possibility of designing a new gene therapy or drug because now we can convert cancerous cells back into their normal state," said Professor Bumsoo Han of Purdue's mechanical engineering, who is also the program leader for the university's Center for Cancer Research, in. Han has also received a courtesy appointment in biomedical engineering, according to the post.
However, if there were a means to turn back the clocks of time, and reprogram the cancerous acinar cells that generate those enzymes, it could reset. For a decade, Purdue's Professor Emeritus Stephen Konieczny of the department of biological sciences has extensively explored the viability of this potent rest button. No, that's not a figure of speech, it's really as simple as that, the whole trick centers on a gene called PTF1a.
Incredibly, the new model overcomes the substantial challenge of accurately capturing the anatomical complexity of the acinus, which is a circular cavity lined with living cells."From an engineering perspective, creating this kind of three-dimensional cavity is not trivial," said Han in the post."So, figuring out a way to build this cavity is an innovation in itself.
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