17,604-patient trial tested Wegovy not for for its heart protective benefits
LONDON – Patients taking Novo Nordisk's Wegovy obesity treatment maintained an average of 10 per cent weight loss after four years, potentially boosting the drugmaker's case to insurers and governments to cover the cost of the effective but expensive drug.
"We see that once the majority of the weight loss is accrued, you don't go back and start to increase in weight if you stay on the drug," he added. Markus Manns, a portfolio manager at Union Investment in Germany and a Novo Nordisk shareholder, told Reuters that the data, which is better than the drug for the same disease from Swiss pharma company Roche "unlocks another $2 billion opportunity" for the company.
Patients in the trial called Select lost an average of nearly 10pc of their total body weight after 65 weeks on Wegovy. That percentage weight-loss was roughly sustained year-on-year until the end of about four years, where weight loss stood at 10.2pc, the company said. The Select study showed that Wegovy reduced the risk of a major cardiovascular event such as a stroke by 20pc in overweight or obese people with a history of heart disease, news that sent Novo shares soaring 13pc to record highs when it was released in August.
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