Some of the mutations identified had not previously been linked with the disease
NEW YORK – Twelve breast cancer genes identified in women of African ancestry in a large study published on Monday may one day help better predict their risk for the disease and highlights potential risk differences from women of European descent.
, or were not as strongly linked as in this new analysis, indicating that genetic risk factors "may differ between females of African and European ancestry," the researchers wrote in Nature Genetics. Black women in the United States have higher rates of breast cancer before age 50, a higher incidence of harder-to-treat breast cancers, and a 42 per cent higher breast cancer death rate than white women, according to the American Cancer Society.
Women in the study carrying all six genes were 4.2 times more likely to be diagnosed with triple-negative breast cancer than those with none or only one of the variants, the study found.
US Black Women Black Women African Ancestry Genetic Mutations European Ancestry BRCA1 BRCA2 Breast Cancer Genetic Testing
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